Process optimization and upscaling

To achieve a constant quantity and quality for your biobased production process, a lot of effort has to be put in optimization and trouble shooting.

To achieve a constant quantity and quality for your biobased production process, a lot of effort has to be put in optimization and trouble shooting.

 

To achieve a constant quantity and quality for your biobased production process, a lot of effort has to be put in optimization and trouble shooting. We offer support by looking into the detail of your process and making a project plan how to improve it. If desirable, optimization of the process can be divided in smaller steps.

Additionally, services can include:

  • Assistance setting up Goals and Objectives in close cooperation with customers
  • Setup and give guidance to consortia
  • Environmental & Regulatory Permitting
  • Setup and implementation of the contract strategy
  • Providing Quick scans
  • Surveys and audits
  • Asset Management / Operational Management / Sourcing en Training
  • Dispute management (Mediation)
  • Improvement maintenance systems
  • Risk / opportunity analysis
  • Temporary project support / sourcing
  • Compliance projects

 

Example: Process optimization and upscaling for fermentation processes

Optimization may consist of:

  • Choice of production organism
  • Selection and parallel testing of improved strains or cultures
  • Identification of critical fermentation parameters such as pH, dissolved oxygen
  • Improved control on the process by analysis of substrate and product
  • Alternative feeding strategies
  • Adjustments to media; defined media
  • Up-scaling (up to 200L)
  • Preparation of the product for further down-stream processing