Process optimization and upscaling

To achieve a constant quantity and quality for your biobased production process, a lot of effort has to be put in optimization and trouble shooting.

To achieve a constant quantity and quality for your biobased production process, a lot of effort has to be put in optimization and trouble shooting. We offer support by looking into the detail of your process and making a project plan how to improve it. If desirable, optimization of the process can be divided in smaller steps.

Additionally, services can include:

• Assistance setting up Goals and Objectives in close cooperation with customers
• Setup and give guidance to consortia
• Environmental & Regulatory Permitting
• Setup and implementation of the contract strategy
• Providing Quick scans
• Surveys and audits
• Asset Management / Operational Management / Sourcing en Training
• Dispute management (Mediation)
• Improvement maintenance systems
• Risk / opportunity analysis
• Temporary project support / sourcing
• Compliance projects

Example: Process optimization and upscaling for fermentation processes

Optimization may consist of:

• Choice of production organism
• Selection and parallel testing of improved strains or cultures
• Identification of critical fermentation parameters such as pH, dissolved oxygen
• Improved control on the process by analysis of substrate and product
• Alternative feeding strategies
• Adjustments to media; defined media
• Up-scaling (up to 200L)
• Preparation of the product for further down-stream processing